ThisdiagramprovidedbytheShanghaiInstituteofCeramics(SIC)oftheChineseAcademyofSciences,showshowanimmunomodulatorymulticellularscaffoldbasedonmanganesesilicate(MS)nanoparticlesisusedforintegratedtendon-to-boneregeneration.(Xinhua)SHANGHAI,March18(Xinhua)--AChineseresearchteamhasdevelopedamulticellularscaffoldbasedoninorganicbioceramicsfortreatingtendon-to-boneinjuries.Restrictionofmotoractivityduetolossofnaturalstructureisamajorcauseofdecreasedlifequalityinpatientssufferingfromtendon-to-boneinjuries.Tosolvethisproblem,theresearchteam,ledbytheShanghaiInstituteofCeramics(SIC)oftheChineseAcademyofSciences,combinedmanganesesilicate(MS)nanoparticleswithtendon/bone-relatedcellstoconstructanimmunomodulatorymulticellularscaffoldtoachieveintegratedtendon-to-boneregeneration.Thescaffoldnotonlydemonstrateddiversebiologicalactivitiesinvitro,butalsoachievedimmuneregulation,multi-tissueintegrationregenerationandmotorfunctionrecoveryinavarietyofanimalmodelsofrotatorcuffinjury.Thestudyprovidesanewconceptforachievingimmunomodulationandintegratedregenerationoftendon-boneandothertissueinterfaces,saidWuChengtiewiththeSIC,wholedtheresearch.ThestudywasrecentlypublishedinthejournalScienceAdvances.Editor:DisclaimerTheviewsandopinionsexpressedinthisarticlearethoseoftheauthor's,GMW.cnmakesnorepresentationsastoaccuracy,suitability,orvalidityofanyinformationonthissiteandwillnotbeliableforanyerrors,omissions,ordelaysinthisinformation.